(Odds Ratio of Fatal Motor Vehicle Crash Associated With Various Substances) "The estimated odds ratios of fatal motor vehicle crashes associated with different drugs reported in this population-based case-control analysis are generally consistent with previous studies (Bedard et al., 2007; Brault et al., 2004; Laumon et al., 2005; Mathijssen and Houwing, 2005; Movig et al., 2004; Mura et al., 2003). For instance, in a case-control study conducted in the Netherlands, Movig et al.
(High-Potency Cannabis and Titration of Dosage Among Experienced Users) "Although experienced young adult cannabis users with a preference for stronger joints titrated their THC exposure to some extent by inhaling less smoke, in general more potent cannabis was used in higher dosages leading to a higher THC exposure compared to users preferring lower potency cannabis.
(High-Potency Cannabis and Potential For Developing Dependence) "This study among 98 experienced cannabis smokers is the first naturalistic study to examine whether users of cannabis with high THC concentration titrate the psychoactive effects by using lower doses and/or by reduced inhalation, and whether cannabis smoking behaviour (topography) predicts cannabis dependence severity independently of total THC exposure.
(Smoking Behavior and Potential for Developing Dependence on Cannabis) "Differences in cannabis smoking behaviour may also represent different risks for cannabis dependence independently of total THC exposure. Similar to cigarette smokers [16,21–24], cannabis smokers typically gradually decrease the puff volume and puff duration during the course of one joint, whereas puff velocity and interpuff interval gradually increase .
(Monitoring The Future Survey on the Potential Impact of Legalization On Youth Marijuana Use) "Marijuana is one drug that is affected by some very specific policies, including medicalization and legalization of recreational use by adults. The effects on youth behaviors and attitudes of recent changes in a number of states will need to be carefully monitored in future years.
(Known Therapeutic Benefits From Medicinal Cannabinoids) "Cannabis preparations exert numerous therapeutic effects. They have antispastic, analgesic, antiemetic, neuroprotective, and anti-inflammatory actions, and are effective against certain psychiatric diseases. Currently, however, only one cannabis extract is approved for use. It contains THC and CBD [cannabidiol] in a 1:1 ratio and was licensed in 2011 for treatment of moderate to severe refractory spasticity in multiple sclerosis (MS).
(Comparison of Results from Standardized Field Sobriety Tests (SFST) and Roadside Saliva Drug Tests in Detecting Cannabis Use) "The SFST was mildly sensitive to the effects of cannabis alone. A dose of 400 ?g/kg body weight THC significantly increased the percentage of participants displaying impairments in OLS compared to baseline performance from 21 to 50 %. THC also increased percentage of individuals showing impairment on HGN from 0 to 15 %, relative to baseline, but this change only approached statistical significance.
(Comparison of Results from Standardized Field Sobriety Tests (SFST) and Roadside Drug Testing)
"Methods Twenty heavy cannabis users (15 males and 5 females; mean age, 24.3 years) participated in a double-blind, placebo-controlled study assessing percentage of impaired individuals on the SFST and the sensitivity of two oral fluid devices. Participants received alcohol doses or
alcohol placebo in combination with 400 ?g/kg body weight THC. We aimed to reach peak blood alcohol concentration values of 0.5 and 0.7 mg/mL.
(Prevalence of Marijuana Use Among Full-Time Workers in the US)
" An estimated 6.4 percent, or 7.3 million, of full-time workers reported use of marijuana during the past month (Tables 2.2 and 2.3).
" Adults aged 26 to 34 were only about half as likely as 18- to 25-year-olds to be past month marijuana users (8.0 vs. 15.9 percent). Past month use of marijuana was lower with increasing age (Table 2.2).
" The prevalence of past month marijuana use was higher for males than females (7.9 vs. 4.3 percent, respectively) (Table 2.2).
(Estimated Prevalence of Problem Cannabis Use in Spain) "As shown in Table 4.5 above, in 2010, a total of 4.6% of Spain’s students within the 14-18 age range might be involved in a use of drugs which may cause them some type of problem. The prevalence of problem use, calculated by means of the CAST [Cannabis Abuse Screening Test] scale, reveals an upward trend in Spain within the 2006-2010 time period, despite a slight decline in cannabis use having been record for the same period.