Medical Marijuana - Research - 12-22-10

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Cannabis and Diabetes

(Cannabinoids and Diabetic Cardiomyopathy) "Remarkably, CBD [Cannabidiol] attenuated myocardial dysfunction, cardiac fibrosis, oxidative/nitrative stress, inflammation, cell death, and interrelated signaling pathways. Furthermore, CBD also attenuated the high glucose-induced increased reactive oxygen species generation, nuclear factor-


Rajesh, Mohanraj; Mukhopadhyay,Partha; Batkai, Sandor; Patel, Vivek; Patel, Keita; Matsumoto, Shingo; Kashiwaya, Yoshihiro; Horvath, Béla; Mukhopadhyay, Bani; Becker, Lauren; Hasko, György; Liaudet, Lucas; Wink, David A.; Veves, Aristidis; Mechoulam, Raphael; Pacher, Pal, "Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy," Journal of the American College of Cardiology (San Diego, CA: American College of Cardiology Foundation: December 2010) Vol. 56, No. 25, p. 2115.

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