"Alcohol and tobacco consumption levels are by far those which cause the most serious extent of damage, either on the health or social level, or with regard to potential dependency."

Source

Report to the European Monitoring Center on Drugs and Drug Addiction by the Reitox National Focal Point of France, l'Observatoire francais des drogues et des toxicomanies (OFDT), "France Drug Situation 2000" (Paris, France: OFDT and EMCDDA, December 2000), p. 29.
http://www.emcdda.europa.eu/a…