Dark Web and the Street Drug Market

"Highly anonymized, elusive, and unregulated, the Dark Web is an ideal landscape for vendors selling illicit substances. The substances, in addition to the markets themselves, that are available on the Dark Web at any given time are difficult to predict. To offer insight into and characterize Dark Web markets, we conducted a study of the substances available on the Dark Web, both historically—between 2012 and 2019—and at present, between 2022 and 2023.

Changes in Dark Web Drug Markets

"Descriptive analysis of the data collected through both the literature review and data scraping on the Dark Web indicated varying periods of volatility in the availability and distribution of psychoactive substances. Notably, no major changes were apparent in the distribution of substances, on average, between 2012 and 2019, as reported in the literature.

People Incarcerated in the US

"ƒ The U.S. prison population was 1,230,100 at yearend 2022, a 2% increase from yearend 2021 (1,205,100).

"ƒ The number of females in state or federal prison increased almost 5% from yearend 2021 (83,700) to yearend 2022 (87,800).

"ƒ Nine states and the BOP increased their total prison populations by over 1,000 persons from yearend 2021 to yearend 2022.

"ƒ State correctional authorities had jurisdiction over 1,039,500 persons sentenced to at least 1 year in prison in 2022, while the BOP had legal authority over 146,100 persons with similar sentences.

Receipt of Opioid Use Disorder Treatments Prior to Fatal Overdoses and Comparison to No Treatment

"The findings revealed that exposures to MOUD, even if not continued throughout the six-month exposure period was associated with reduced risk of a fatal poisoning compared to non-MOUD forms of treatment and no treatment exposure. It is also clear that risk of death associated with exposure to non-MOUD forms of treatment was no less than that for no treatment; indeed, non-MOUD treatment might have produced worse outcomes than no treatment.

Use of Prescription Fentanyl and Illegally Made Fentanyl in the US According to the National Survey on Drug Use and Health

"Among people aged 12 or older in 2022, 0.4 percent (or 991,000 people) misused fentanyl in the past year, including 0.1 percent of adolescents aged 12 to 17, 0.2 percent of young adults aged 18 to 25, and 0.4 percent of adults aged 26 or older (Table A.12B). Corresponding estimated numbers of people who misused fentanyl in the past year were 34,000 adolescents aged 12 to 17, 75,000 young adults aged 18 to 25, and 882,000 adults aged 26 or older.

"IMF [Illegally Made Fentanyl] Use

Development of Prescribed Safer Supply in Canada

"The extremely potent and toxic nature of ISOs [Illicit/Synthetic Opioids] has rendered them the primary cause of overdose fatalities while consequently presenting major challenges for the menu of available interventions. Many existing interventions have mostly aimed at either manipulating the drug use environment to be safer (e.g., supervised consumption) or reactively treating underlying drug use disorders (OAT) or overdoses (naloxone).

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