Global Burden of Disease, Mental Health, and Substance Use Disorders

"In 2010, mental and substance use disorders accounted for 183.9 million DALYs [Disability-Adjusted Life Years] (95% UI 153.5 million–216.7 million), or 7.4% (6.2–8.6) of all DALYs worldwide. Such disorders accounted for 8.6 million YLLs [Years of Life Lost] (6.5 million–12.1 million; 0.5% [0.4–0.7] of all YLLs) and 175.3 million YLDs [Years Lived with Disability] (144.5 million–207.8 million; 22.9% [18.6–27.2] of all YLDs). Mental and substance use disorders were the leading cause of YLDs worldwide. Depressive disorders accounted for 40.5% (31.7–49.2) of DALYs caused by mental and substance use disorders, with anxiety disorders accounting for 14.6% (11.2–18.4), illicit drug use disorders for 10.9% (8.9–13.2), alcohol use disorders for 9.6% (7.7–11.8), schizophrenia for 7.4% (5.0–9.8), bipolar disorder for 7.0% (4.4–10.3), pervasive developmental disorders for 4.2% (3.2–5.3), childhood behavioural disorders for 3.4% (2.2–4.7), and eating disorders for 1.2% (0.9–1.5). DALYs varied by age and sex, with the highest proportion of total DALYs occurring in people aged 10–29 years. The burden of mental and substance use disorders increased by 37.6% between 1990 and 2010, which for most disorders was driven by population growth and ageing."